The endometrium, the soft and vascular inner lining of the uterus, plays a crucial role in achieving and sustaining pregnancy. It forms the nurturing base where the embryo implants and begins early development. Any abnormality in endometrial growth, structure, or receptivity can lead to infertility or recurrent pregnancy loss.
At Kiran Infertility Center (KIC), our team — led by Dr. Kiran Sekhar, Dr. Samit Sekhar, Dr. Pratima Sekhar, and Dr. Sravanti Sadu — offers advanced diagnostics and evidence-based therapies to help women overcome endometrial-related infertility and achieve successful conception. Our specialists also guide patients seeking thin endometrium treatment in Hyderabad. focusing on improving uterine blood flow, balanced nutrition, and hormone support alongside medical options like PRP therapy and hormonal regulation for optimal endometrial health.
Endometrium and Infertility
The endometrium naturally regenerates and changes throughout the menstrual cycle. Under the influence of estrogen, it thickens in preparation for embryo implantation, and progesterone further matures it during the luteal phase.
If fertilization occurs, this lining supports the embryo and facilitates placental formation. When pregnancy doesn’t occur, it sheds as part of menstruation.
An optimal endometrial thickness (around 7.5–8 mm or more) is typically ideal for successful implantation, whether in natural conception or assisted reproduction such as IVF. Let’s have a deep look into Endometrium and Infertility
Common Endometrial Causes of Infertility
1. Thin Endometrium
A thin endometrial lining (less than 7 mm) can make it difficult for an embryo to implant or sustain itself, leading to infertility or early miscarriage.
Common causes include:
• Asherman’s Syndrome (uterine adhesions and scarring)
• Chronic infections like endometritis or tuberculosis
• Repeated uterine surgeries or trauma (such as curettage or D&C)
• Hormonal imbalance or age-related decline in estrogen levels
A thin endometrium has reduced blood flow and poor cellular development, lowering the chances of pregnancy.
At Kiran Infertility Center, specialists focus on personalized hormonal therapy and regenerative procedures like PRP treatment to restore healthy endometrial growth.
2. Thick or Hypertrophic Endometrium
An excessively thick endometrium (more than 15 mm) may also cause fertility issues.
Possible causes include:
• Hormonal imbalance, especially excess estrogen
• Presence of endometrial polyps or submucosal fibroids
Such conditions can interfere with normal implantation and may result in abnormal uterine bleeding.
Under the expert guidance of IVF specialists, patients at KIC undergo precise diagnosis through hysteroscopy or ultrasound, ensuring targeted treatment for better reproductive outcomes.
3. Endometrial Adhesions and Infections
Uterine infections or scar tissue can damage the endometrium, reducing its ability to support an embryo.
Diagnosis: These issues are identified through hysteroscopy or endometrial biopsy.
Treatment:
At Kiran Infertility Center, hysteroscopic surgery is performed to remove adhesions, followed by antibiotic therapy to treat infections. This helps restore a healthy uterine cavity and improves implantation potential.
4. Fluid Accumulation in the Endometrium
Sometimes, fluid buildup inside the uterus, often due to hydrosalpinx (fluid-filled fallopian tubes), can hinder embryo implantation and reduce IVF success rates.
In such cases, our surgical team perform laparoscopic procedures to remove or block the affected tubes, ensuring a better uterine environment for embryo transfer.
Advanced Treatments to Improve Endometrial Fertility
At Kiran Infertility Center, advanced and evidence-based treatments are offered to enhance endometrial health and receptivity:
1. Hysteroscopic Surgery:
Removal of polyps, fibroids, and adhesions to improve the uterine environment.
2. Intrauterine Device (IUD):
Placed after surgery to prevent adhesions from reforming.
3. Targeted Antibiotic Therapy:
Used to treat chronic uterine infections confirmed through biopsy.
4. Platelet-Rich Plasma (PRP) Therapy:
A highly effective treatment performed by our fertility specialists to promote endometrial regeneration and improve thickness in women with thin linings.
5. Hormonal Therapy:
Customized estrogen and progesterone support to enhance endometrial development before embryo transfer.
6. Surgical Management of Hydrosalpinx:
Removal or clipping of the affected fallopian tubes to eliminate fluid accumulation.
7. Assisted Reproductive Technologies (ART):
When medical or surgical treatments alone are not sufficient, IVF or ICSI procedures are recommended, ensuring a higher chance of conception.
Frequently Asked Questions (FAQs)
Q1: What is the function of the endometrium in fertility?
A: The endometrium is where the embryo implants and develops. Its thickness and receptivity are vital for a successful pregnancy.
Q2: How does a thin endometrium affect fertility?
A: A thin lining provides an insufficient environment for implantation, leading to infertility or recurrent pregnancy loss.
Q3: Can a very thick endometrium cause infertility?
A: Yes. When the endometrium becomes excessively thick due to hormonal imbalance, fibroids, or polyps, it can prevent proper embryo attachment.
Q4: What causes endometrial adhesions?
A: Adhesions often result from uterine surgeries, infections, or trauma that lead to scar tissue formation.
Q5: Are there effective treatments for thin endometrium?
A: Yes. Treatments include hysteroscopic adhesiolysis, PRP therapy, hormonal medication, and in some cases, IVF or ART for improved pregnancy success.
Q6: How is fluid in the uterus treated?
A: If fluid results from hydrosalpinx, laparoscopic removal or clipping of the fallopian tubes is performed to restore fertility potential.
Conclusion
The health and receptivity of the endometrium play an essential role in every woman’s fertility journey. Whether the issue is a thin lining, thickened endometrium, or uterine adhesions, timely diagnosis and treatment can make a significant difference.
At Kiran Infertility Center, the expert team — Dr. Kiran Sekhar, Dr. Samit Sekhar, Dr. Pratima Sekhar, and Dr. Sravanti Sadu — combine advanced medical science with compassionate care to help every woman achieve her dream of motherhood.