How do immunologic factors contribute to infertility?
In both men and women, immunologic factors can lead to infertility.
This can happen due to activation of the pathogenic self-reactive T cells or depletion of the Suppressor (Regulator) T cells. Immunologic factors contribute to infertility in both men and women, and gonadal failure has been linked with premature ovarian failure in women and azoospermia in men.
The anti-sperm antibodies or ASA are also responsible for infertility issues.
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