How do immunologic factors contribute to infertility?

How do immunologic factors contribute to infertility?

In both men and women, immunologic factors can lead to infertility.
This can happen due to activation of the pathogenic self-reactive T cells or depletion of the Suppressor (Regulator) T cells. Immunologic factors contribute to infertility in both men and women, and gonadal failure has been linked with premature ovarian failure in women and azoospermia in men.
The anti-sperm antibodies or ASA are also responsible for infertility issues.

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