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Kiran Infertility Center Hyderabad

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Kiran Infertility Center – Hyderabad

Sai Kiran Hospitals - Unit of Kiran Infertility Center

Understanding Pre-implantation Genetic Diagnosis

Pre-implantation Genetic Diagnosis (PGD or PIGD) is an advanced genetic testing procedure used during In Vitro Fertilization (IVF) to help identify embryos with specific genetic or chromosomal conditions before pregnancy begins.

What is PGD?

PGD involves carefully examining the chromosomes and genes of embryos created through IVF before they are transferred to the uterus. The main goal is to help identify embryos that are free of specific genetic disorders you may be concerned about, allowing for the transfer of an embryo with the best possible chance of developing into a healthy baby.

How Does PGD Work?

The process begins with a standard IVF cycle to create embryos. Around day 5 or 6 of development, when embryos reach the blastocyst stage, a few cells are gently removed for testing. This biopsy is performed with precision to minimize impact on the embryo. The cells are then analysed in a specialized laboratory to screen for specific genetic conditions or chromosomal abnormalities.

Who Can Benefit from PGD?

PGD may be recommended for couples at risk of passing on inherited genetic conditions, including:

  • Single Gene Disorders: Such as cystic fibrosis, sickle cell disease, Huntington’s disease, or muscular dystrophy.
  • Chromosomal Conditions: Such as balanced translocations, which can affect embryo development. 

This technology is particularly valuable for couples who have a known family history of genetic diseases and wish to avoid passing these conditions to their children.

Understanding Pre-implantation Genetic Diagnosis

PGD and Pregnancy Success

By identifying chromosomally normal embryos, PGD can help improve the chances of a successful pregnancy and reduce the risk of miscarriage associated with chromosomal abnormalities. This allows our medical team to select the most viable embryo for transfer.

Important Information

Please note that PGD in India is strictly regulated and is not permitted for gender selection or non-medical reasons. Our clinic fully adheres to these ethical guidelines and legal requirements.

Take the Next Step Towards Building Your Family
Every family-building journey is unique. Our experienced fertility and genetic care
team provides advanced reproductive technologies, personalised guidance and
compassionate support based on your individual needs and family history.

Our fertility team is here to answer your questions, discuss your treatment options, and provide the guidance and support you need throughout your family-building journey. Email us at info@kiranivfgenetic.com to start the conversation.

FAQs About Pre-implantation Genetic Diagnosis
Please see below for answers to some of the most common questions about Preimplantation Genetic Diagnosis.

Frequently Asked Questions About Pre-implantation Genetic Diagnosis

Pre-implantation Genetic Diagnosis (PGD or PIGD) is a genetic testing procedure performed during an IVF cycle to help identify embryos affected by specific genetic or chromosomal conditions before an embryo is transferred to the uterus. It may be considered when there is a known risk of passing an inherited condition to a child.

PGD begins with an IVF cycle to create embryos. When an embryo reaches the blastocyst stage, usually around day 5 or 6 of development, a small number of cells are carefully removed for genetic testing. The sample is analyzed in a specialized laboratory to look for specific genetic conditions or chromosomal abnormalities, while the embryo is managed according to the IVF laboratory protocol.

PGD may be considered for couples who have a known risk of passing on certain inherited genetic conditions. These may include single-gene disorders such as cystic fibrosis, sickle cell disease, Huntington’s disease or muscular dystrophy, as well as certain chromosomal abnormalities, including balanced translocations. Your fertility and genetic specialists will assess your individual circumstances and family history to determine whether PGD may be appropriate.

PGD can help identify embryos that do not carry the specific genetic or chromosomal condition being tested for, allowing the medical team to make a more informed decision about embryo selection. In appropriate cases, this may help reduce the risk of transferring an embryo affected by the condition being tested for. However, PGD cannot guarantee implantation, pregnancy or the birth of a healthy baby, and its benefits depend on the specific condition and individual circumstances.

No. PGD in India is strictly regulated and cannot be used for gender selection or other non-medical purposes. PGD may be performed for appropriate medical and genetic indications in accordance with applicable Indian laws and regulations. At Kiran Infertility Centre, our team follows the relevant ethical and legal requirements when providing genetic testing as part of fertility treatment.

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